2010 Schedule
Preseason |
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| Result | Date | Opponent | Time | Network |
| L 20-10 | 08/13/10 | at Atlanta Falcons | 7:00 PM | KCTV5 |
| L 20-15 | 08/21/10 | at Tampa Bay Buccaneers | 6:30 PM | KCTV5 |
| L 20-17 | 08/27/10 | Philadelphia Eagles | 7:00 PM | KCTV5 |
| W13-17 | 09/02/10 | Green Bay packers | 7:00 PM | KCTV5 |
Regular Season |
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| Result | Date | Opponent | Time | Network |
| W14-21 | 09/13/10 | San Diego Chargers | 9:15 PM | ESPN |
| W16-14 | 09/19/10 | at Cleveland Browns | 12:00 PM | CBS |
| W10-31 | 09/26/10 | SanFrancisco 49ers | 12:00 PM | FOX |
| 10/03/10 | BYE | |||
| L9-10 | 10/10/10 | at Indianapolis Colts | 12:00 PM | CBS |
| L35-31 | 10/17/10 | at Houston Texans | 12:00 PM | CBS |
| W42-20 | 10/24/10 | Jacksonville Jaguars | 12:00 PM | CBS |
| W13-10 | 10/31/10 | Buffalo Bills | 12:00 PM | CBS |
| L23-20 | 11/07/10 | at Oakland Raiders | 3:15 PM | CBS |
| L49-29 | 11/14/10 | at Denver Broncos | 3:05 PM | CBS |
| W31-13 | 11/21/10 | Arizona Cardinals | 12:00 PM | FOX |
| W42-24 | 11/28/10 | at Seattle Seahawks | 3:05 PM | CBS |
| W6-10 | 12/05/10 | Denver Broncos | 12:00 PM | CBS |
| L 0-31 | 12/12/10 | at San Diego Chargers | 3:15 PM | CBS |
| W27-13 | 12/19/10 | at St Louis Rams | 12:00 PM | CBS |
| W14-34 | 12/26/09 | Tennessee Titans | 12:00 PM | CBS |
| 01/02/11 | Oakland Raiders | 12:00 PM | CBS | |
All times Central and subject to change.